Ivercor 6 Mg is an ectoparasiticide which helps in improving the parasitic infections of eyes, skin, and intestinal tract. It is also used to treat river blindness (onchocerciasis) and strongyloidiasis.
IVERCOR-COVID19 is a citywide governmental COVID-19 prevention program in Itajai, Natal, and Macapa, Brazil. It is a prospective, randomized trial.
Ivermectin’s Role in Public Health Programs
There are very few drugs that can seriously lay claim to the title of ‘Wonder drug’, with penicillin and aspirin perhaps being two of the best known. Ivermectin can definitely be included in this prestigious group, given its tremendous versatility and the enormously positive impact that it has had on the lives of millions of people worldwide.
Its discovery and subsequent use against onchocerciasis, lymphatic filariasis, and malaria, among other diseases, has been a remarkable journey for both the scientists responsible and the public that has benefitted from this amazing drug. Its transformation from an animal health medication to the successful delivery of a life-changing human drug has involved a great deal of hard work, tenacity and vision, along with a fair amount of luck and educated insight.
The discovery and subsequent development of ivermectin has had a major beneficial impact on hundreds of millions of people worldwide, especially the world’s poorest. Its versatility and safety have also made it a hugely important drug in combating various parasitic diseases such as worms, tsetse fly, fleas and ticks.
In addition to this, ivermectin has also been found to have anti-cancer properties as well, due to its ability to inhibit signal transducer and activator of transcription (STAT)-3 in tumor cells. This inhibition causes the cancerous cells to break down, thereby killing them.
Ivermectin’s Safety
Ivermectin has been used in millions of people for over a century to treat parasitic worm infections, including onchocerciasis and lymphatic filariasis. Despite this, the drug is still under debate for its safety in pregnant women. This is due to the fact that the drug causes serious side effects such as eye problems and skin rash in some patients. Additionally, it may cause birth defects in some babies. Fortunately, most of these problems can be avoided by following proper dosage guidelines.
Ivercor 6 Mg is safe when taken as directed. However, you should not take the medication if you have a severe allergic reaction. In addition, you should tell your doctor if you are pregnant or plan to become pregnant. Also, it is important to keep this medicine away from children and pets.
While ivermectin is safe in pregnancy when used correctly, current evidence on this issue is limited and inconclusive. Most of the observational studies are nested within MDA campaigns and thus lack important comparability factors such as age of the mother and history of other pregnancy-related complications. The majority of the studies also have poor methodological quality, such as uncontrolled selection of participants and selective reporting of outcomes. Furthermore, the number of pregnant women exposed to ivermectin in the studies was low and point estimates for the primary outcome had wide confidence intervals that crossed the threshold for statistical significance.
Ivermectin’s Dosage
Ivermectin’s discovery, subsequent use and distribution has involved a unique public-private partnership and the commitment and vision of several key individuals. Its journey from the research laboratories of Merck Laboratories to the communities whose lives it has improved worldwide was marked by scientific uncertainty, conflicting views, frustration and luck, along with an element of sheer individual innovation.
Ivermectin acts by inhibiting glutamate-gated chloride ion channels found in nerves and muscles, paralyzing adult parasites and preventing the release of eggs or microfilariae. It also has inhibitory effects on g-aminobutyric acid receptors in the central nervous system, although entry into the CNS is prevented by the blood-brain barrier.
While the mechanism of ivermectin’s neuroprotective action is not fully understood, it appears to be related to its ability to modulate the function of various cellular pathways, including protein synthesis, cell migration, cell division and cell growth. In addition, ivermectin has been shown to prevent mitochondrial dysfunction and oxidative stress.
It is important to note that the AMA and American Society of Health-System Pharmacists do not support the ordering or prescribing of ivermectin for COVID-19 outside a clinical trial, as it poses significant risk of serious toxicity in humans. The veterinary forms of this medication, which are designed for large animals, have been shown to be highly concentrated and could pose a serious toxicity risk in humans if ingested orally.
Ivercor 6 Mg Side Effects
In a re-purposing of the drug, researchers are exploring its potential to control a range of parasitic diseases that afflict the world’s poorest populations. This approach, known as “deworming” is a powerful tool to combat disease, increase economic productivity and reduce the burden on healthcare systems.
ivermectin’s side effects are relatively mild, but they can occur in some people. These include allergic reactions such as swelling of the eyelids, lips, hands or feet and may be fatal in severe cases. The drug can also cause a rash that spreads quickly over the skin.
It is important to tell your doctor about all medications you take, including prescription and over-the-counter drugs, vitamins/minerals, herbs and supplements. This helps your doctor to determine if ivermectin is safe for you. It is also important to let your doctor know if you have traveled to west or central Africa where there is an increased risk of developing intestinal strongyloidiasis.
Pregnant women should not take ivermectin. It is unknown whether the medication could harm an unborn baby, so women who are pregnant or breastfeeding should not take it. It is important to keep all appointments with your doctor and laboratory tests so that your doctor can monitor your progress. This is especially true if you are taking ivermectin for onchocerciasis or strongyloidiasis. Keeping all appointments will help your treatment to be successful and prevent the development of complications.
